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High-accuracy proteome maps of human body fluids

Alexander Schmidt and Ruedi Aebersold*

Author Affiliations

Institute for Molecular Systems Biology, ETH Zurich, Wolfgang-Pauli-Strasse 16, CH-8093 Zurich, Switzerland

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Genome Biology 2006, 7:242  doi:10.1186/gb-2006-7-11-242

Published: 28 November 2006

Abstract

The proteomes most likely to contain clinically useful disease biomarkers are those of human body fluids. Three recent large-scale proteomic analyses of tears, urine and seminal plasma using the latest mass spectrometric technology will provide useful datasets for biomarker discovery.