Influence of assumed network reliability on LP-score predictions. Influence of the assumed network reliability on the number of pairs with LP-score above 0.5 and the number of interactions among those that are confirmed by crystal structures in our gold standard set or by witnesses. The number of pairs confirmed by the gold standard set remains stable for all network reliability assumptions, and interactions predicted under assumption of a lower network reliability almost always are a subset of the interactions predicted under the assumption of a higher network reliability.
Guimarães et al. Genome Biology 2006 7:R104 doi:10.1186/gb-2006-7-11-r104