|
Highly regulated or reporter metabolites for the three possible pair-wise comparisons between the different carbon sources |
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| Ethanol versus glucose |
Ethanol versus glycerol |
Glycerol versus glucose |
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|
|
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| Reporter metabolite |
n |
P |
Reporter metabolite |
n |
P |
Reporter metabolite |
n |
P |
|
|
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| Acetyl coenzyme A (mitochondrial) |
12 |
2.1E-06 |
Oxaloacetate |
13 |
7.6E-05 |
N-Carbamoyl-L-aspartate |
3 |
1.0E-03 |
| Coenzyme A (mitochondrial) |
14 |
2.6E-06 |
Coenzyme A (mitochondrial) |
14 |
1.2E-04 |
Carbamoyl phosphate |
5 |
1.7E-03 |
| Glyoxylate (glyoxysomal) |
3 |
1.8E-05 |
Glyoxylate (glyoxysomal) |
3 |
2.1E-04 |
2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine |
2 |
2.8E-03 |
| Oxaloacetate |
13 |
9.4E-05 |
Acetyl coenzyme A (mitochondrial) |
12 |
2.7E-04 |
Glycogen |
2 |
2.8E-03 |
| Acetyl coenzyme A (glyoxysomal) |
2 |
1.1E-04 |
Acetyl coenzyme A (glyoxysomal) |
2 |
4.2E-04 |
Maltose |
6 |
2.9E-03 |
| Coenzyme A (glyoxysomal) |
2 |
1.1E-04 |
Coenzyme A (glyoxysomal) |
2 |
4.2E-04 |
Maltose (extracellular) |
6 |
2.9E-03 |
| Oxaloacetate (mitochondrial) |
11 |
4.4E-04 |
Oxaloacetate (mitochondrial) |
11 |
4.3E-04 |
L-glutamine |
16 |
3.1E-03 |
| Carnitine |
2 |
4.9E-04 |
2-Oxoglutarate (mitochondrial) |
9 |
4.9E-04 |
α-D-glucose 1-phosphate |
4 |
3.4E-03 |
| O-acetylcarnitine |
2 |
4.9E-04 |
Citrate |
1 |
5.6E-04 |
ATP |
94 |
3.7E-03 |
| Propanoyl-coenzyme A |
3 |
6.1E-04 |
Phosphoenolpyruvate |
6 |
8.5E-04 |
(R)-3-Hydroxy-3-methyl-2-oxobutanoate (mitochondrial) |
2 |
4.4E-03 |
| Maltose |
6 |
7.0E-04 |
Fumarate (mitochondrial) |
3 |
8.6E-04 |
(R)-2,3-dihydroxy-3-methylbutanoate (mitochondrial) |
2 |
4.4E-03 |
| Maltose (extracellular) |
6 |
7.0E-04 |
α-D-glucose 1-phosphate |
4 |
9.5E-04 |
Carbon dioxide |
42 |
4.7E-03 |
| O-acetylcarnitine (mitochondrial) |
2 |
9.0E-04 |
Citrate (mitochondrial) |
5 |
1.3E-03 |
S-acetyldihydrolipoamide (mitochondrial) |
2 |
5.1E-03 |
| Carnitine (mitochondrial) |
2 |
9.0E-04 |
Carnitine |
2 |
1.9E-03 |
Carbon dioxide (mitochondrial) |
16 |
6.0E-03 |
| O-acetylcarnitine (glyoxysomal) |
2 |
9.0E-04 |
O-acetylcarnitine |
2 |
1.9E-03 |
ADP |
64 |
1.2E-02 |
|
Shown are highly regulated or reporter metabolites for the three possible pair-wise comparisons between the different carbon sources, according to Patil and Nielsen [23]. 'n' denotes the number of neighbors of the reporter metabolite (the number of reactions in which it participates). | ||||||||
David et al. Genome Biology 2006 7:R108 doi:10.1186/gb-2006-7-11-r108 |
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