Schematic genomic organization of the human and mouse chemokine superfamily. (a) Major-cluster chemokines; (b) mini-cluster chemokines; (c) non-cluster chemokines. Solid arrows indicate chemokine genes and their transcriptional orientation; red, green and pink arrows indicate inflammatory, homeostatic and dual function chemokine genes, respectively, and gray arrows indicate pseudogenes. Duplication units in the major clusters are indicated by open yellow arrows. This figure is based on the NCBI 36 and 35 assemblies of the human and mouse genomes . A gap indicates a region not yet covered by the genome sequencing consortiums, while a dashed line denotes a similar region of more than 1 Mb.
Zlotnik et al. Genome Biology 2006 7:243 doi:10.1186/gb-2006-7-12-243