Table 1 |
|||||
|
The human ideogram at the 550 band resolution showing the location of fragile sites and evolutionary breakpoints |
|||||
|
Chromosomal band |
Type fs |
EB |
Chromosomal band |
Type fs |
EB |
|
|
|||||
|
10p11.1 |
No fs |
No EB |
22q13.3b |
r-fs |
EB |
|
10p11.2 |
No fs |
EB |
2p11.1 |
No fs |
No EB |
|
10p12.1 |
No fs |
EB |
2p11.2b |
r-fs |
EB |
|
10p12.2 |
No fs |
No EB |
2p12 |
No fs |
EB |
|
10p12.3 |
No fs |
EB |
2p13b |
c-fs |
EB |
|
10p13 |
No fs |
EB |
2p14 |
No fs |
EB |
|
10p14 |
No fs |
EB |
2p15 |
No fs |
EB |
|
10p15 |
No fs |
EB |
2p16 |
c-fs |
EB |
|
10q11.1 |
No fs |
No EB |
2p21 |
No fs |
EB |
|
10q11.2a |
c-fs |
EB |
2p22 |
No fs |
EB |
|
10q21.1a |
c-fs |
EB |
2p23 |
No fs |
EB |
|
10q21.2a |
c-fs |
EB |
2p24 |
c-fs |
No EB |
|
10q21.3a |
c-fs |
EB |
2p25.1 |
No fs |
No EB |
|
10q22.1a |
c-fs |
EB |
2p25.2 |
No fs |
No EB |
|
10q22.2 |
No fs |
EB |
2p25.3 |
No fs |
EB |
|
10q22.3 |
No fs |
EB |
2q11.1 |
No fs |
No EB |
|
10q23.1 |
No fs |
EB |
2q11.2a |
r-fs |
EB |
|
10q23.2 |
No fs |
EB |
2q12 |
No fs |
EB |
|
10q23.3a |
r-fs |
EB |
2q13a |
r-fs |
EB |
|
10q24.1 |
No fs |
EB |
2q14.1 |
No fs |
EB |
|
10q24.2 |
No fs |
EB |
2q14.2 |
No fs |
EB |
|
10q24.3 |
No fs |
EB |
2q14.3 |
No fs |
EB |
|
10q25.1 |
No fs |
EB |
2q21.1 |
No fs |
EB |
|
10q25.2 |
c-fs and r-fs |
No EB |
2q21.2 |
No fs |
EB |
|
10q25.3 |
No fs |
No EB |
2q21.3 |
c-fs |
EB |
|
10q26.1a |
c-fs |
EB |
2q22 |
r-fs |
EB |
|
10q26.2 |
No fs |
EB |
2q23 |
No fs |
EB |
|
10q26.3 |
No fs |
No EB |
2q24.1 |
No fs |
No EB |
|
11p11.1 |
No fs |
EB |
2q24.2 |
No fs |
EB |
|
11p11.21 |
No fs |
No EB |
2q24.3 |
No fs |
No EB |
|
11p11.22 |
No fs |
EB |
2q31a |
c-fs |
No EB |
|
11p12 |
No fs |
No EB |
2q32.1a |
c-fs |
EB |
|
11p13 |
c-fs |
EB |
2q32.2 |
No fs |
EB |
|
11p14 |
c-fs |
EB |
2q32.3 |
No fs |
EB |
|
11p15.1b |
c-fs and r-fs |
EB |
2q33a |
c-fs |
EB |
|
11p15.2 |
No fs |
EB |
2q34 |
No fs |
EB |
|
11p15.3 |
No fs |
No EB |
2q35 |
No fs |
EB |
|
11p15.4 |
No fs |
EB |
2q36 |
No fs |
EB |
|
11p15.5 |
No fs |
EB |
2q37.1 |
No fs |
EB |
|
11q11 |
No fs |
No EB |
2q37.2 |
No fs |
EB |
|
11q12 |
No fs |
EB |
2q37.3b |
c-fs |
EB |
|
11q13.1b |
c-fs |
EB |
3p11 |
No fs |
No EB |
|
11q13.2b |
c-fs |
No EB |
3p12 |
No fs |
EB |
|
11q13.3b |
c-fs and r-fs |
EB |
3p13 |
No fs |
No EB |
|
11q13.4b |
c-fs |
EB |
3p14.1 |
No fs |
EB |
|
11q13.5b |
c-fs |
EB |
3p14.2 |
c-fs |
No EB |
|
11q14.1 |
No fs |
EB |
3p14.3 |
No fs |
EB |
|
11q14.2a |
c-fs |
No EB |
3p21.1 |
No fs |
No EB |
|
11q14.3 |
No fs |
EB |
3p21.2 |
No fs |
EB |
|
11q21 |
No fs |
No EB |
3p21.3 |
No fs |
EB |
|
11q22.1 |
No fs |
EB |
3p22 |
No fs |
EB |
|
11q22.2 |
No fs |
EB |
3p23 |
No fs |
EB |
|
11q22.3 |
No fs |
EB |
3p24 |
c-fs |
EB |
|
11q23.3a |
c-fs and r-fs |
No EB |
3p25 |
No fs |
EB |
|
11q23.2 |
No fs |
No EB |
3p26 |
No fs |
No EB |
|
11q23.1 |
No fs |
EB |
3q11.1 |
No fs |
No EB |
|
11q24 |
No fs |
EB |
3q11.2 |
No fs |
EB |
|
11q25 |
No fs |
No EB |
3q12 |
No fs |
EB |
|
12p11.1 |
No fs |
No EB |
3q13.1 |
No fs |
No EB |
|
12p11.2 |
No fs |
EB |
3q13.2 |
No fs |
EB |
|
12p12.1 |
No fs |
No EB |
3q13.3 |
No fs |
EB |
|
12p12.2 |
No fs |
No EB |
3q21 |
No fs |
EB |
|
12p12.3 |
No fs |
No EB |
3q22 |
No fs |
EB |
|
12p13.3 |
No fs |
EB |
3q23 |
No fs |
EB |
|
12p13.2 |
No fs |
No EB |
3q24 |
No fs |
EB |
|
12p13.1 |
No fs |
No EB |
3q25.1 |
c-fs |
No EB |
|
12q11 |
No fs |
No EB |
3q25.2 |
c-fs |
No EB |
|
12q12 |
No fs |
No EB |
3q25.3 |
c-fs |
EB |
|
12q13.1a |
r-fs |
EB |
3q26.1 |
No fs |
EB |
|
12q13.2 |
No fs |
EB |
3q26.2 |
No fs |
EB |
|
12q13.3 |
No fs |
EB |
3q26.3 |
No fs |
EB |
|
12q14 |
No fs |
EB |
3q27a |
c-fs |
EB |
|
12q15 |
No fs |
No EB |
3q28 |
No fs |
No EB |
|
12q21.1 |
No fs |
EB |
3q29 |
No fs |
EB |
|
12q21.2 |
No fs |
EB |
4p11 |
No fs |
No EB |
|
12q21.3a |
c-fs |
No EB |
4p12 |
No fs |
EB |
|
12q22 |
No fs |
EB |
4p13 |
No fs |
EB |
|
12q23 |
No fs |
EB |
4p14 |
No fs |
No EB |
|
12q24.1b |
c-fs and r-fs |
EB |
4p15.1b |
c-fs |
No EB |
|
12q24.2b |
c-fs and r-fs |
No EB |
4p15.2b |
c-fs |
No EB |
|
12q24.31b |
c-fs |
EB |
4p15.3b |
c-fs |
EB |
|
12q24.32b |
c-fs |
No EB |
4p16a |
c-fs |
EB |
|
12q24.33b |
c-fs |
No EB |
4q11 |
No fs |
No EB |
|
13p13 |
No fs |
No EB |
4q12 |
c-fs |
EB |
|
13p12 |
No fs |
No EB |
4q13.1 |
No fs |
No EB |
|
13p11.2 |
No fs |
No EB |
4q13.2 |
No fs |
No EB |
|
13p11.1 |
No fs |
No EB |
4q13.3 |
No fs |
EB |
|
13q11 |
No fs |
No EB |
4q21.1 |
No fs |
EB |
|
13q12.1 |
No fs |
EB |
4q21.2 |
No fs |
EB |
|
13q12.2 |
No fs |
No EB |
4q21.3 |
No fs |
No EB |
|
13q12.3 |
No fs |
No EB |
4q22 |
c-fs |
EB |
|
13q13 |
c-fs |
EB |
4q23 |
No fs |
No EB |
|
13q14.1 |
No fs |
EB |
4q24 |
No fs |
No EB |
|
13q14.2 |
No fs |
EB |
4q25 |
No fs |
No EB |
|
13q14.3 |
No fs |
EB |
4q26 |
No fs |
EB |
|
13q21.1b |
c-fs |
No EB |
4q27 |
No fs |
EB |
|
13q21.2b |
c-fs |
No EB |
4q28 |
No fs |
EB |
|
13q21.3b |
c-fs |
No EB |
4q31.1 |
c-fs |
EB |
|
13q22 |
No fs |
No EB |
4q31.2 |
No fs |
EB |
|
13q31 |
No fs |
EB |
4q31.3 |
No fs |
EB |
|
13q32 |
c-fs |
No EB |
4q32 |
No fs |
EB |
|
13q33 |
No fs |
EB |
4q33 |
No fs |
EB |
|
13q34 |
No fs |
No EB |
4q34 |
No fs |
EB |
|
14p13 |
No fs |
No EB |
4q35 |
No fs |
EB |
|
14p12 |
No fs |
No EB |
5p11 |
No fs |
No EB |
|
14p11.2 |
No fs |
No EB |
5p12 |
No fs |
EB |
|
14p11.1 |
No fs |
No EB |
5p13.1a |
c-fs |
No EB |
|
14q11.1 |
No fs |
No EB |
5p13.2a |
c-fs |
No EB |
|
14q11.2 |
No fs |
EB |
5p13.3a |
c-fs |
No EB |
|
14q12 |
No fs |
No EB |
5p14b |
c-fs |
No EB |
|
14q13 |
No fs |
EB |
5p15.1 |
No fs |
EB |
|
14q21 |
No fs |
EB |
5p15.2 |
No fs |
EB |
|
14q22 |
No fs |
EB |
5p15.3 |
No fs |
EB |
|
14q23a |
c-fs |
EB |
5q11.1 |
No fs |
No EB |
|
14q24.1 |
c-fs |
No EB |
5q11.2 |
No fs |
EB |
|
14q24.2 |
No fs |
No EB |
5q12 |
No fs |
EB |
|
14q24.3 |
No fs |
No EB |
5q13.1 |
No fs |
EB |
|
14q31 |
No fs |
No EB |
5q13.2 |
No fs |
EB |
|
14q32.1 |
No fs |
No EB |
5q13.3 |
No fs |
EB |
|
14q32.2 |
No fs |
No EB |
5q14 |
No fs |
EB |
|
14q32.3 |
No fs |
EB |
5q15 |
c-fs |
EB |
|
15p13 |
No fs |
No EB |
5q21b |
c-fs |
EB |
|
15p12 |
No fs |
No EB |
5q22 |
No fs |
EB |
|
15p11.2 |
No fs |
No EB |
5q23.1 |
No fs |
No EB |
|
15p11.1 |
No fs |
No EB |
5q23.2 |
No fs |
No EB |
|
15q11.1 |
No fs |
No EB |
5q23.3 |
No fs |
EB |
|
15q11.2 |
No fs |
EB |
5q31.1b |
c-fs |
EB |
|
15q12 |
No fs |
EB |
5q31.2 |
No fs |
No EB |
|
15q13 |
No fs |
EB |
5q31.3 |
No fs |
No EB |
|
15q14 |
No fs |
EB |
5q32 |
No fs |
EB |
|
15q15 |
No fs |
EB |
5q33.1 |
No fs |
EB |
|
15q21.1 |
No fs |
EB |
5q33.2 |
No fs |
EB |
|
15q21.2 |
No fs |
No EB |
5q33.3 |
No fs |
EB |
|
15q21.3 |
No fs |
No EB |
5q34 |
No fs |
EB |
|
15q22.1a |
c-fs |
No EB |
5q35.1b |
r-fs |
EB |
|
15q22.2a |
c-fs |
No EB |
5q35.2b |
r-fs |
EB |
|
15q22.3a |
c-fs |
EB |
5q35.3b |
r-fs |
EB |
|
15q23 |
No fs |
EB |
6p11.1 |
No fs |
No EB |
|
15q24 |
No fs |
EB |
6p11.2 |
No fs |
EB |
|
15q25 |
No fs |
EB |
6p12 |
No fs |
EB |
|
15q26.1 |
No fs |
EB |
6p21.1 |
No fs |
EB |
|
15q26.2 |
No fs |
No EB |
6p21.2 |
No fs |
EB |
|
15q26.3 |
No fs |
EB |
6p21.3 |
No fs |
EB |
|
16p11.1 |
No fs |
No EB |
6p22.1 |
No fs |
EB |
|
16p11.2 |
No fs |
EB |
6p22.2 |
c-fs |
EB |
|
16p12a |
r-fs |
EB |
6p22.3 |
No fs |
EB |
|
16p13.1b |
r-fs |
EB |
6p23a |
r-fs |
No EB |
|
16p13.2 |
No fs |
No EB |
6p24 |
No fs |
No EB |
|
16p13.3 |
No fs |
EB |
6p25a |
c-fs |
No EB |
|
16q11.1 |
No fs |
No EB |
6q11 |
No fs |
No EB |
|
16q11.2 |
No fs |
No EB |
6q12 |
No fs |
EB |
|
16q12.1 |
No fs |
EB |
6q13a |
c-fs |
EB |
|
16q12.2 |
No fs |
EB |
6q14 |
No fs |
EB |
|
16q13 |
No fs |
EB |
6q15 |
c-fs |
EB |
|
16q21 |
No fs |
EB |
6q16.1 |
No fs |
EB |
|
16q22a |
c-fs and r-fs |
EB |
6q16.2 |
No fs |
No EB |
|
16q23a |
c-fs |
EB |
6q16.3 |
No fs |
EB |
|
16q24 |
No fs |
No EB |
6q21a |
c-fs |
No EB |
|
17p11.1 |
No fs |
No EB |
6q22.1 |
No fs |
EB |
|
17p11.2 |
No fs |
EB |
6q22.2 |
No fs |
No EB |
|
17p12 |
r-fs |
EB |
6q22.3 |
No fs |
EB |
|
17p13 |
No fs |
EB |
6q23.1 |
No fs |
No EB |
|
17q11.1 |
No fs |
No EB |
6q23.2 |
No fs |
EB |
|
17q11.2 |
No fs |
EB |
6q23.3 |
No fs |
No EB |
|
17q12 |
No fs |
EB |
6q24 |
No fs |
EB |
|
17q21.1 |
No fs |
EB |
6q25.1 |
No fs |
EB |
|
17q21.2 |
No fs |
EB |
6q25.2 |
No fs |
EB |
|
17q21.3 |
No fs |
EB |
6q25.3 |
No fs |
EB |
|
17q22 |
No fs |
No EB |
6q26b |
c-fs |
No EB |
|
17q23 |
c-fs |
EB |
6q27 |
No fs |
EB |
|
17q24 |
No fs |
EB |
7p11.1 |
No fs |
No EB |
|
17q25 |
No fs |
EB |
7p11.2a |
r-fs |
EB |
|
18p11.1 |
No fs |
No EB |
7p12 |
No fs |
EB |
|
18p11.2 |
No fs |
EB |
7p13a |
c-fs |
EB |
|
18p11.32 |
No fs |
EB |
7p14 |
c-fs |
EB |
|
18p11.31 |
No fs |
No EB |
7p15.1 |
No fs |
No EB |
|
18q11.1 |
No fs |
No EB |
7p15.2 |
No fs |
EB |
|
18q11.2 |
No fs |
EB |
7p15.3 |
No fs |
EB |
|
18q12.1 |
No fs |
No EB |
7p21 |
No fs |
EB |
|
18q12.2 |
c-fs |
EB |
7p22b |
c-fs |
EB |
|
18q12.3 |
No fs |
EB |
7q11.1b |
c-fs |
No EB |
|
18q21.1 |
No fs |
EB |
7q11.21b |
c-fs |
No EB |
|
18q21.2 |
No fs |
No EB |
7q11.22b |
c-fs |
EB |
|
18q21.3a |
c-fs |
EB |
7q11.23b |
c-fs |
EB |
|
18q22 |
r-fs |
EB |
7q21.1 |
No fs |
EB |
|
18q23 |
No fs |
EB |
7q21.2 |
c-fs |
EB |
|
19p11 |
No fs |
No EB |
7q21.3 |
No fs |
EB |
|
19p12 |
No fs |
EB |
7q22b |
c-fs |
EB |
|
19p13.1b |
r-fs |
EB |
7q31.1 |
No fs |
EB |
|
19p13.2b |
r-fs |
EB |
7q31.2 |
c-fs |
No EB |
|
19p13.3b |
r-fs |
EB |
7q31.3 |
No fs |
EB |
|
19q11 |
No fs |
No EB |
7q32 |
c-fs |
EB |
|
19q12 |
No fs |
EB |
7q33 |
No fs |
EB |
|
19q13.1 |
c-fs |
EB |
7q34 |
No fs |
EB |
|
19q13.2 |
c-fs |
EB |
7q35 |
No fs |
EB |
|
19q13.3 |
c-fs |
EB |
7q36b |
c-fs |
EB |
|
19q13.4 |
c-fs |
EB |
8p11.1 |
No fs |
No EB |
|
1p11 |
No fs |
No EB |
8p11.2 |
No fs |
EB |
|
1p12 |
No fs |
No EB |
8p12 |
No fs |
EB |
|
1p13.1 |
No fs |
EB |
8p21.1 |
No fs |
EB |
|
1p13.2 |
No fs |
EB |
8p21.2 |
No fs |
EB |
|
1p13.3 |
No fs |
EB |
8p21.3 |
No fs |
EB |
|
1p21 |
c-fs and r-fs |
EB |
8p22 |
No fs |
EB |
|
1p22.1 |
c-fs |
EB |
8p23.1 |
No fs |
EB |
|
1p22.2 |
c-fs |
EB |
8p23.2 |
No fs |
No EB |
|
1p22.3 |
c-fs |
EB |
8p23.3 |
No fs |
EB |
|
1p31.1 |
c-fs |
EB |
8q11.1 |
No fs |
No EB |
|
1p31.2 |
c-fs |
EB |
8q11.21 |
No fs |
EB |
|
1p31.3 |
c-fs |
No EB |
8q11.23 |
No fs |
EB |
|
1p32.3b |
c-fs |
EB |
8q12 |
No fs |
EB |
|
1p32.1b |
c-fs |
No EB |
8q13 |
No fs |
EB |
|
1p32.2b |
c-fs |
EB |
8q21.1 |
No fs |
EB |
|
1p33 |
No fs |
No EB |
8q21.2 |
No fs |
EB |
|
1p34.1 |
No fs |
No EB |
8q21.3 |
No fs |
No EB |
|
1p34.2 |
No fs |
EB |
8q22.1a |
c-fs |
EB |
|
1p34.3 |
No fs |
EB |
8q22.2 |
No fs |
No EB |
|
1p35 |
No fs |
EB |
8q22.3 |
r-fs |
EB |
|
1p36.1b |
c-fs |
EB |
8q23 |
No fs |
EB |
|
1p36.2b |
c-fs |
EB |
8q24.1 |
c-fs and r-fs |
EB |
|
1p36.3b |
c-fs |
EB |
8q24.2 |
No fs |
No EB |
|
1q11 |
No fs |
No EB |
8q24.3b |
c-fs |
No EB |
|
1q12 |
c-fs |
No EB |
9p11 |
No fs |
No EB |
|
1q21.1b |
c-fs |
No EB |
9p12 |
No fs |
No EB |
|
1q21.2b |
c-fs |
No EB |
9p13 |
No fs |
EB |
|
1q21.3b |
c-fs |
EB |
9p21 |
c-fs and r-fs |
EB |
|
1q22 |
No fs |
No EB |
9p22 |
No fs |
No EB |
|
1q23 |
No fs |
EB |
9p23 |
No fs |
EB |
|
1q24 |
No fs |
EB |
9p24 |
No fs |
EB |
|
1q25 |
c-fs |
EB |
9q11 |
No fs |
No EB |
|
1q31 |
c-fs |
EB |
9q12b |
c-fs |
No EB |
|
1q32.1 |
No fs |
EB |
9q13 |
No fs |
No EB |
|
1q32.2 |
No fs |
EB |
9q21.1 |
No fs |
No EB |
|
1q32.3 |
No fs |
EB |
9q21.2 |
No fs |
EB |
|
1q41 |
No fs |
EB |
9q21.3 |
No fs |
EB |
|
1q42.1b |
c-fs |
EB |
9q22.1 |
c-fs |
EB |
|
1q42.2b |
c-fs |
No EB |
9q22.2 |
No fs |
EB |
|
1q42.3b |
c-fs |
EB |
9q22.3 |
No fs |
EB |
|
1q43 |
No fs |
EB |
9q31 |
No fs |
EB |
|
1q44b |
c-fs |
EB |
9q32a |
c-fs and r-fs |
EB |
|
20p11.1 |
No fs |
No EB |
9q33 |
No fs |
EB |
|
20p11.2 |
r-fs |
EB |
9q34.1 |
No fs |
EB |
|
20p12 |
c-fs |
EB |
9q34.2 |
No fs |
No EB |
|
20p13 |
No fs |
EB |
9q34.3 |
No fs |
EB |
|
20q11.1 |
No fs |
No EB |
Xp11.1 |
No fs |
No EB |
|
20q11.2 |
No fs |
EB |
Xp11.21 |
No fs |
No EB |
|
20q12 |
No fs |
No EB |
Xp11.22 |
No fs |
EB |
|
20q13.1 |
No fs |
EB |
Xp11.23 |
No fs |
EB |
|
20q13.2 |
No fs |
No EB |
Xp11.3 |
No fs |
EB |
|
20q13.3 |
No fs |
No EB |
Xp11.4 |
No fs |
No EB |
|
21p13 |
No fs |
No EB |
Xp21.3 |
No fs |
No EB |
|
21p12 |
No fs |
No EB |
Xp21.2 |
No fs |
No EB |
|
21p11.2 |
No fs |
No EB |
Xp21.1 |
No fs |
EB |
|
21p11.1 |
No fs |
No EB |
Xp22.1 |
No fs |
EB |
|
21q11 |
No fs |
EB |
Xp22.2 |
No fs |
No EB |
|
21q21.1 |
No fs |
No EB |
Xp22.3 |
c-fs |
No EB |
|
21q21.2 |
No fs |
No EB |
Xq11 |
No fs |
EB |
|
21q22.1 |
No fs |
EB |
Xq12.1 |
No fs |
No EB |
|
21q22.2 |
No fs |
No EB |
Xq12.2 |
No fs |
No EB |
|
21q22.3 |
No fs |
EB |
Xq13 |
No fs |
EB |
|
22p13 |
No fs |
No EB |
Xq21.1 |
No fs |
EB |
|
22p12 |
No fs |
No EB |
Xq21.2 |
No fs |
No EB |
|
22p11.2 |
No fs |
No EB |
Xq21.3 |
No fs |
EB |
|
22p11.1 |
No fs |
No EB |
Xq22.1 |
c-fs |
EB |
|
22q11.1 |
No fs |
No EB |
Xq22.2 |
No fs |
EB |
|
22q11.2 |
No fs |
EB |
Xq22.3 |
No fs |
EB |
|
22q12.1 |
No fs |
EB |
Xq23 |
No fs |
EB |
|
22q12.2a |
c-fs |
EB |
Xq24 |
No fs |
EB |
|
22q12.3 |
No fs |
EB |
Xq25 |
No fs |
EB |
|
22q13.1b |
r-fs |
EB |
Xq26 |
No fs |
EB |
|
22q13.2b |
r-fs |
EB |
Xq27 |
c-fs and r-fs |
EB |
|
Xq28 |
r-fs |
No EB |
|||
|
|
|||||
|
All rare fragile sites (r-fs) and common fragile sites (c-fs) described by Schwartz and coworkers [39] and the evolutionary breakpoints (EBs) were plotted on the ideogram. Note that human chromosome Y is not included in the study. aFragile sites situated in bands comprising ≥ 6000 base pairs (bp) of tandem repeats in windows of 0.250 megabases (Mb). bFragile sites in bands with ≥ 10,000 bp of tandem repeats in windows of 0.250 Mb. |
|||||
|
Ruiz-Herrera et al. Genome Biology 2006 7:R115 doi:10.1186/gb-2006-7-12-r115 |
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