Table 2

GO terms associated with TE-rich human genes

Over-represented TE types


GO term

Description

Alu

L1

L2

LTR

DNA transp.

MIR


Molecular function

N

MCS

IG


GO:0008009

Chemokine activity

-

-

-

-

-

9

-0.91*

-0.66

GO:0005125

Cytokine activity

-

-

-

-

-

24

-0.42

-0.13

GO:0001584

Rhodopsin-like receptor activity

-

-

-

-

-

19

-0.44

0.31

GO:0042379

Chemokine receptor binding

-

-

-

-

-

9

-0.91*

-0.66

GO:0005102

Receptor binding

-

-

-

-

-

38

-0.45

-0.03

GO:0001664

G-protein-coupled receptor binding

-

-

-

-

-

9

-0.91*

-0.66

Biological process

GO:0050874

Organismal physiological process

-

-

-

-

-

89

-0.57*

0.01

GO:0009607

Response to biotic stimulus

-

-

-

-

-

70

-0.69*

0.36

GO:0006955

Immune response

-

-

-

-

-

60

-0.67*

0.23

GO:0009611

Response to wounding

-

-

-

-

-

31

-0.73*

0.11

GO:0006954

Inflammatory response

-

-

-

-

-

24

-0.79*

0.06

GO:0006952

Defense response

-

-

-

-

-

66

-0.7*

0.3

GO:0045087

Innate immune response

-

-

-

-

-

26

-0.78*

0.07

GO:0016064

Humoral defense mechanism

-

-

-

-

-

14

-0.65

0.24

GO:0009617

Response to bacteria

-

-

-

-

-

13

-0.83*

0.34

GO:0009613

Response to pest, pathogen or parasite

-

-

-

-

-

47

-0.72*

0.21

GO:0043207

Response to external biotic stimulus

-

-

-

-

-

51

-0.74*

0.16

GO:0006950

Response to stress

-

-

-

-

-

53

-0.72*

0.16

GO:0042742

Defense response to bacteria

-

-

-

-

-

9

-0.98*

0.36

GO:0009605

Response to external stimulus

-

-

-

-

-

65

-0.76*

0.19

GO:0009620

Response to fungi

-

-

-

-

-

6

-1*

0.91

GO:0009628

Response to abiotic stimulus

-

-

-

-

-

28

-0.83*

0.55

GO:0042221

Response to chemical substance

-

-

-

-

-

27

-0.83*

0.7

GO:0050896

Response to stimulus

-

-

-

-

-

85

-0.71*

0.31

GO:0006968

Cellular defense response

-

-

-

-

-

14

-0.64

-0.14

GO:0007267

Cell-cell signaling

-

-

-

-

-

37

-0.26

-0.32

GO:0042330

Taxis

-

-

-

-

-

17

-0.78*

-0.1

GO:0006935

Chemotaxis

-

-

-

-

-

17

-0.78*

-0.1

GO:0030574

Collagen catabolism

-

-

-

-

-

7

-0.69

-0.77


Significant differences are marked with an asterisk. DNA transp., DNA transposon; N, number of contributing genes; MCS, fractional intronic MCS density deviation (see text); IG, fractional igTEna deviation (see text).

Sironi et al. Genome Biology 2006 7:R120   doi:10.1186/gb-2006-7-12-r120

Open Data