gd and Tl regulate ftz stripe location. Quantitative comparison of ftz expression (a) between mutant embryos derived from gd7 homozygous mothers and wild-type-like embryos derived from gd7 heterozygous mothers and (b) between mutant embryos derived from Tl10B homozygous mothers and wild-type-like embryos derived from Tl10B heterozygous mothers; both show lateral orthographic projections indicating the position of each of the seven stripes in wild-type-like embryos (blue stripes) and mutant embryos (red stripes). All embryos were from stages 5:25-75%. The confidence intervals, embryo orientation, and scales are as described in Figure 4. Shifts in the ftz expression boundaries are consistent with dorsalized (gd) and ventralized (Tl) nuclear flow, respectively. (c) The effects of disrupting the d/v system on stripe curvature and placement in single embryo images, shown in a lateral view. The stripes in the mutant embryos (right) clearly differ from those in the wild-type-like embryos (left), but because of small differences in embryo orientation and shape it is difficult to draw a precise understanding of how stripe locations have changed from such raw image data.
Keränen et al. Genome Biology 2006 7:R124 doi:10.1186/gb-2006-7-12-r124