Table 4 |
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|
DDI-PPI mapping based on both single domain PPIs and the structural DDIs |
|||||
|
Organisma |
E. coli |
yeast |
worm |
fly |
human |
|
|
|||||
|
Number of PPIs |
6,934 |
24,699 |
5,315 |
24,703 |
28,800 |
|
Number of PPIs with known domains (N) |
6,038 |
18,202 |
3,351 |
14,939 |
25,004 |
|
Number of PPIs to which DDIs could be mapped (n) (%; n/N*100) |
1,234 (20%) |
5,048 (28%) |
860 (26%) |
3,983 (27%) |
7,991 (32%) |
|
|
|||||
|
a Organism labeling: yeast: S. cerevisiae, worm: C. elegans, fly: D. melanogaster. DDI, domain-domain interaction; PPI, protein-protein interaction. |
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|
Itzhaki et al. Genome Biology 2006 7:R125 doi:10.1186/gb-2006-7-12-r125 |
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