Genome Biology

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Prospective health care: the second transformation of medicine

Ralph Snyderman* and Jason Langheier

Genome Biology 2006, 7:104 doi:10.1186/gb-2006-7-2-104

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Systems medicine: the future of medical genomics and healthcare

Charles Auffray, Zhu Chen, Leroy Hood Genome Med 2009, 1:2 (20 January 2009)

Systems approaches to medicine will transform the way drugs are developed and will enable medicine to become predictive, personalized, preventive and participatory.