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Sex-specific gene expression in preimplantation mouse embryos

Guy S Eakin and Anna-Katerina Hadjantonakis*

Author Affiliations

Developmental Biology Program, Sloan-Kettering Institute, New York, NY 10021, USA

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Genome Biology 2006, 7:205  doi:10.1186/gb-2006-7-2-205

Published: 1 March 2006

Abstract

The 3.5-day-old blastocyst-stage mouse embryo consists of two tissues and contains approximately 60 cells. This tiny structure has now been observed to express nearly 600 genes in a sex-specific fashion, including at least one gene (Rhox/Pem) expressed only in females from their paternal X chromosome.