Two-way hierarchical clustering of the RAW 264.7 macrophage. (a) Signaling pathway responses and (b) cytokine release after single ligand stimulations. Average linkage clustering was performed using un-centered Pearson's correlation metrics on log-transformed and variance-normalized data. Data are averages over the different time points and across repeated experiments. Red = positive change; green = negative change.
Pradervand et al. Genome Biology 2006 7:R11 doi:10.1186/gb-2006-7-2-r11