Figure 3.

Correlation coefficients between signaling responses and cytokine release. Pearson's correlation coefficients were computed for each pair of signaling responses and cytokines using data from single- and double-ligand stimulations. Data from TLR ligand stimulation were (a) included in the procedure or (b) excluded from the procedure. Data were log-transformed and variance-normalized. Significance of correlations was assessed following a t distribution. Heat maps were produced from significant correlation coefficients (red = positive correlation; green = negative correlation).