Table 2

Cytokine gene regulation

Cytokine
Signaling pathways/transcription factors

G-CSF
NF-κB, C/EBPβ, Oct, post-transcriptional regulation
IL-1α
NF-κB, AP-1, Sp1
IL-6
NF-κB, AP-1, Sp1, IRF-1, C/EBPβ
IL-10
C/EBPβ, C/EBPδ, Sp1, cAMP/PKA
MIP-1α
NF-κB, Ets, C/EBPβ, cAMP/PKA, posttranscriptional regulation
RANTES
NF-κB, AP-1, IRF-1, IRF-3
TNFα
Egr-1, Ets/Elk, NF-κB, c-jun/ATF-2, cAMP/PKA, post-transcriptional regulation (p38 dependent)

References can be found in the text.

Pradervand et al. Genome Biology 2006 7:R11   doi:10.1186/gb-2006-7-2-r11

Open Data