Genome Biology

official impact factor 6.89

Open Access Highly Access

Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites

Tobias J Sargeant, Matthias Marti, Elisabet Caler, Jane M Carlton, Ken Simpson, Terence P Speed and Alan F Cowman*

Genome Biology 2006, 7:R12 doi:10.1186/gb-2006-7-2-r12

Accesses  

  • Last 30 days: 98 accesses
  • Last year: 1008 accesses
  • All time: 8650 accesses

Cited by

BioMed Central: 11 citations

Research   Open Access Highly Accessed

Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

Antoine Claessens, Ashfaq Ghumra, Archna P Gupta, Sachel Mok, Zbynek Bozdech, J Alexandra Rowe Malaria Journal 2011, 10:180 (30 June 2011)

The authors have extended a MicroArray resource by adding members of different variant surface antigen (VSA) gene families and then using this new chip to identify the genes involved with a specific adherence phenotype (rosetting). This confirms that cytoadherence studies have been right to concentrate on PfEMP1.

Research article   Open Access Highly Accessed

Phylogenomic analyses of malaria parasites and evolution of their exported proteins

Christian Pick, Ingo Ebersberger, Tobias Spielmann, Iris Bruchhaus, Thorsten Burmester BMC Evolutionary Biology 2011, 11:167 (15 June 2011)

Research   Open Access

Core genome components and lineage specific expansions in malaria parasites Plasmodium

Hong Cai, Jianying Gu, Yufeng Wang BMC Genomics 2010, 11(Suppl 3):S13 (1 December 2010)

Research   Open Access

Redefining the expressed prototype SICAvar gene involved in Plasmodium knowlesi antigenic variation

Stacey A Lapp, Cindy C Korir, Mary R Galinski Malaria Journal 2009, 8:181 (31 July 2009)

Research   Open Access

The effect of mimicking febrile temperature and drug stress on malarial development

Ratchaneewan Aunpad, Sangdao Somsri, Kesara Na-Bangchang, Rachanee Udomsangpetch, Mathirut Mungthin, Poom Adisakwattana, Wanna Chaijaroenkul Annals of Clinical Microbiology and Antimicrobials 2009, 8:19 (12 June 2009)

Research   Open Access

Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins

Marissa Vignali, Anastasia McKinlay, Douglas J LaCount, Rakesh Chettier, Russell Bell, Sudhir Sahasrabudhe, Robert E Hughes, Stanley Fields Malaria Journal 2008, 7:211 (20 October 2008)

The paper looks at the interactions of the gene product of ETRAMP5 and human lipoproteins, specifically ApoA1, ApoB and ApoE. This interaction is based on data generated by a yeast-2-hybrid screen of P. falciparum and human liver and cerebellum libraries.

Review   Open Access Highly Accessed

Heterologous expression of plasmodial proteins for structural studies and functional annotation

Lyn-Marie Birkholtz, Gregory Blatch, Theresa L Coetzer, Heinrich C Hoppe, Esmaré Human, Elizabeth J Morris, Zoleka Ngcete, Lyndon Oldfield, Robyn Roth, Addmore Shonhai, Linda Stephens, Abraham I Louw Malaria Journal 2008, 7:197 (1 October 2008)

A comprehensive overview of methods that have been used more or less successful to generate recombinant Plasmodium proteins either for large scale biochemical and structural studies or for functional studies.

Research   Open Access

A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum

Matthias Scholz, Martin J Fraunholz Genome Biology 2008, 9:R88 (27 May 2008)

A mathematical model of the intraerythrocytic developmental cycle identifies a delay between subtelomeric and central chromosomal gene activities in the malaria parasite, Plasmodium falciparum.

Research article   Open Access Highly Accessed

Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles

Ruchi Verma, Ajit Tiwari, Sukhwinder Kaur, Grish C Varshney, Gajendra PS Raghava BMC Bioinformatics 2008, 9:201 (16 April 2008)

Research   Open Access Highly Accessed

A highly conserved segmental duplication in the subtelomeres of Plasmodium falciparum chromosomes varies in copy number

Bobo W Mok, Ulf Ribacke, Ellen Sherwood, Mats Wahlgren Malaria Journal 2008, 7:46 (7 March 2008)

The subtelomeric regions of the 14 chromosomes are species-specific, highly polymorphic and consist of a patchworks of repetitive blocks. Many families of variable genes, including var genes, are located in this regions.

Methodology   Open Access Highly Accessed

Comparative proteomic analysis of metabolically labelled proteins from Plasmodium falciparum isolates with different adhesion properties

Yang Wu, Alister Craig Malaria Journal 2006, 5:67 (3 August 2006)

A methodology paper showing how proteomics can be applied to the characterization of parasite molecules involved in cytoadherence.