Genome Biology

official impact factor 6.89

Open Access Research

Modulation of the transcription regulatory program in yeast cells committed to sporulation

Gilgi Friedlander1, Daphna Joseph-Strauss1, Miri Carmi1, Drora Zenvirth2, Giora Simchen2* and Naama Barkai1*

Author Affiliations

1 Departments of Molecular Genetics and Physics of Complex System, Weizmann Institute of Science, Rehovot 76100, Israel

2 Department of Genetics, The Hebrew University of Jerusalem, Jerusalem 91904, Israel

For all author emails, please log on.

Genome Biology 2006, 7:R20 doi:10.1186/gb-2006-7-3-r20

Published: 8 March 2006

Additional files

Additional File 1:

A checklist containing minimum information about a microarray experiment. (MIAME)

Format: DOC Size: 76KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional File 2:

Figure S1 shows polarized expression during sporulation and RTG. Figure S2 shows the expression pattern of IME2 and SMK1. Figure S3 shows a matrix of pairwise correlations that exemplifies the general metabolic response to glucose.

Format: PDF Size: 81KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional File 3:

Table S1 includes a list of early sporulation genes. Table S2 includes a complete list of genes used in Figure 3d of the paper. Table S3 lists examples of genes that according to their expression during RTG are regulated by the mitotic cell cycle. Table S4 lists genes that are induced during RTG (20 min after the transfer). Table S5 lists genes that are induced during RTG (immediately after the transfer). Table S6 lists homologous genes which are induced during sporulation or RTG. Table S7 lists middle sporulation genes that are repressed upon transfer to YPD. Table S8 lists insulated middle sporulation genes. Table S9 lists the 936 genes used for Figure 6a. Table S10 lists rRNA-processing genes. Table S11 lists gluconeogenesis genes. Table S12 lists genes that encode ribosomal proteins. Table S13 lists genes induced in a time-dependent manner. Table S14 lists genes that are induced in response to YPD in committed cells. Table S15 lists genes that are repressed in response to YPD in committed cells. Table S16 includes a list of the yeast strains used in the present study. Table S17 includes the composition of the media used in the present study.

Format: PDF Size: 402KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional File 4:

Normalized data of the present study (in log2 ratios)

Format: ZIP Size: 5.7MB Download file

Open Data

Additional File 5:

A matlab program that enables the expression data discussed in this article to be viewed. Also contains a help file: 'ViewModules help.pdf'

Format: ZIP Size: 9MB Download file

Open Data