Table 1 |
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|
Sequence similarities among selected fungal kinetochore proteins of point CEN |
||||||
| Location |
Complex |
Protein |
Ubiquitous |
Point CEN specific |
Similarity* |
Identity* |
|
|
||||||
| DNA-binding |
Monomer |
Mif2 |
+ |
65% |
23% |
|
| ? |
Sgt1 |
+ |
74% |
28% |
||
| CBF3 |
Cep3 |
+ |
65% |
14% |
||
| Ctf13 |
+ |
53% |
9% |
|||
| Ndc10 |
+ |
48% |
10% |
|||
| Linker layer |
COMA |
Mcm21 |
+ |
45% |
7% |
|
| Ctf19 |
+ |
47% |
7% |
|||
| Ame1 |
+ |
45% |
9% |
|||
| Okp1 |
+ |
51% |
7% |
|||
| MIND |
Nnf1 |
+ |
67% |
14% |
||
| Nsl1 |
+ |
69% |
15% |
|||
| NDC80 |
Ndc80 |
+ |
73% |
20% |
||
| Spc24 |
+ |
63% |
6% |
|||
| SPC105 |
Spc105 |
+ |
48% |
5% |
||
| Ydr532C |
+ |
52% |
6% |
|||
| ? |
Chl4 |
+ |
52% |
11% |
||
| ? |
Ctf3 |
+ |
51% |
6% |
||
| ? |
Nkp1† |
+ |
55% |
6% |
||
| ? |
Nkp2† |
+ |
63% |
6% |
||
| ? |
Mcm16 |
+ |
52% |
7% |
||
| ? |
Mcm22 |
+ |
53% |
4% |
||
| ? |
Iml3‡ |
+ |
24% |
6% |
||
| ? |
Cnn1 |
+ |
40% |
4% |
||
| MT-binding |
DASH |
Ask1 |
+ |
43% |
11% |
|
| Dam1 |
+ |
54% |
6% |
|||
| Regulatory |
? |
Bub3 |
+ |
65% |
18% |
|
| ? |
Mad2 |
+ |
98% |
54% |
||
|
|
||||||
|
*As determined from the proteins in S. cerevisiae, C. glabrata, E. gossyppii and K. lactis. †Instead of E. gossypii the sequences were derived from the very closely related S. kluyveri. ‡Similarity was determined from proteins of the point CEN containing S. cerevisiae, S. kudriavzevii, K. waltii and S. kluyveri. |
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|
Meraldi et al. Genome Biology 2006 7:R23 doi:10.1186/gb-2006-7-3-r23 |
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