Diagram of EGU algorithm. The algorithm considers all exons predicted by GENSCAN and Ensembl as potential exons of a final CDS, and examines exon boundaries to assemble a new gene model. If exons from GENSCAN and Ensembl have different boundaries, the algorithm extends the exon boundary to include all nucleotides of the ab initio and comparative predictions. Subsequently, the ORF-selection algorithm (described in the text) chooses the best translatable reading frame to yield the final ReAnoCDS05 gene model.
Li et al. Genome Biology 2006 7:R24 doi:10.1186/gb-2006-7-3-r24