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Opinion

Metabolic cycle, cell cycle, and the finishing kick to Start

Bruce Futcher

Author affiliations

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA

Citation and License

Genome Biology 2006, 7:107  doi:10.1186/gb-2006-7-4-107

Published: 26 April 2006

Abstract

Slowly growing budding yeast store carbohydrate, then liquidate it in late G1 phase of the cell cycle, superimposing a metabolic cycle on the cell cycle. This metabolic cycle may separate biochemically incompatible processes. Alternatively it may provide a burst of energy and material for commitment to the cell cycle. Stored carbohydrate could explain the size requirement for cells passing the Start point.