Minireview
TANGOing along the protein secretion pathway
University Medical Center Utrecht, The Cell Microscopy Center, Department of Cell Biology and Institute of Biomembranes, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
Genome Biology 2006, 7:213 doi:10.1186/gb-2006-7-4-213
Published: 28 April 2006Abstract
Although the organization and functions of the constitutive secretory pathway have been intensively studied for decades, a recent genome-wide RNAi screen in Drosophila cells has identified about 100 genes encoding novel so-called TANGO proteins (for transport and Golgi organization) that may be direct regulators of various aspects of protein exocytosis or secretion.
