Genome Biology

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Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors

Chad J Creighton, Kevin E Cordero, Jose M Larios, Rebecca S Miller, Michael D Johnson, Arul M Chinnaiyan, Marc E Lippman and James M Rae*

Genome Biology 2006, 7:R28 doi:10.1186/gb-2006-7-4-r28

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Research article   Open Access

Meta-analysis of estrogen response in MCF-7 distinguishes early target genes involved in signaling and cell proliferation from later target genes involved in cell cycle and DNA repair

Vidhya Jagannathan, Marc Robinson-Rechavi BMC Systems Biology 2011, 5:138 (30 August 2011)

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Dynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer

Karen J Taylor, Andrew H Sims, Liang Liang, Dana Faratian, Morwenna Muir, Graeme Walker, Barbara Kuske, J Michael Dixon, David A Cameron, David J Harrison, Simon P Langdon Breast Cancer Research 2010, 12:R39 (22 June 2010)

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Pregnancy in the mature adult mouse does not alter the proportion of mammary epithelial stem/progenitor cells

Kara L Britt, Howard Kendrick, Joseph L Regan, Gemma Molyneux, Fiona-Ann Magnay, Alan Ashworth, Matthew J Smalley Breast Cancer Research 2009, 11:R20 (23 April 2009)

No significant differences exist in stem/progenitor cell numbers between mammary epithelium isolated from mature adult mice that had been through pregnancy at nine weeks old, and age-matched virgin mice.

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Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate

Howard Kendrick, Joseph L Regan, Fiona-Ann Magnay, Anita Grigoriadis, Costas Mitsopoulos, Marketa Zvelebil, Matthew J Smalley BMC Genomics 2008, 9:591 (8 December 2008)

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Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers

Christina Yau, Christopher C Benz Breast Cancer Research 2008, 10:R61 (17 July 2008)

An investigation into the effect of oxidative stress on estrogen and estrogen receptor-regulated gene expression identified a subset of oxidant-sensitive genes associated with poor prognosis in ER+ primary breast cancer.

Short communication   Free

Do classical oestrogen markers predict for clinical response to endocrine therapy?

William R Miller Breast Cancer Research 2007, 9(Suppl 2):S19 (20 December 2007)

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Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers

Christina Yau, Vita Fedele, Ritu Roydasgupta, Jane Fridlyand, Alan Hubbard, Joe W Gray, Karen Chew, Shanaz H Dairkee, Dan H Moore, Francesco Schittulli, Stefania Tommasi, Angelo Paradiso, Donna G Albertson, Christopher C Benz Breast Cancer Research 2007, 9:R59 (12 September 2007)

Epigenetic transcriptome changes, more than genotypic variation, account for age-associated differences in the incidence and prognosis of sporadic hormone-dependant breast cancer, according to microarray study.

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A gene transcription signature associated with hormone independence in a subset of both breast and prostate cancers

Chad J Creighton BMC Genomics 2007, 8:199 (28 June 2007)