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Reference based annotation with GeneMapper

Sourav Chatterji1 email and Lior Pachter2 email

1Department of Computer Science, University of California at Berkeley, Berkeley, CA, 94720, USA

2Department of Mathematics, University of California at Berkeley, Berkeley, CA 94720, USA

author email corresponding author email

Genome Biology 2006, 7:R29doi:10.1186/gb-2006-7-4-r29

Published: 5 April 2006

Subject areas: Bioinformatics, Genome studies

Abstract

We introduce GeneMapper, a program for transferring annotations from a well annotated genome to other genomes. Drawing on high quality curated annotations, GeneMapper enables rapid and accurate annotation of newly sequenced genomes and is suitable for both finished and draft genomes. GeneMapper uses a profile based approach for mapping genes into multiple species, improving upon the standard pairwise approach. GeneMapper is freely available for academic use.


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