Figure 7.

Phylogenetic conservation of the WW ligand motifs within yeast proteins. (a) Positions of primary sequence motifs within S. cerevisiae Aat2, Ymr171c, Ylr392c, Prp2, and Yjl084c. (b) Logo representations [68] of the conserved region within the set of orthologs. The number of orthologs in each set is indicated. Gray dashed boxes highlight the conserved motifs; numbers indicate the position of the motif within the S. cerevisiae protein. Histograms represent the level of conservation of all S. cerevisiae X-X-x-X sequence determinants within the set of orthologs. Colored circles mark the bins that contain the PPxY, PPxF and LPxY motifs.