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RNA at the steering wheel

Sabine Schmitt and Renato Paro email

Zentrum für Molekulare Biologie Heidelberg (ZMBH), University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany

author email corresponding author email

Genome Biology 2006, 7:218doi:10.1186/gb-2006-7-5-218

Published: 26 May 2006

Subject areas: Cell biology, Development, Molecular biology, Genetics, Model organisms

Abstract

Expression of the genetic information encoded in our genomes is usually regulated by proteins interacting with the DNA. In some cases, however, noncoding RNAs transcribed from DNA control elements cooperate with histone-modifying enzymes to regulate gene expression, as has recently been shown for noncoding RNA originating from Polycomb- and Trithorax-group response elements.


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