Genome Biology
Volume 7
Issue 5 |
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MinireviewRNA interference pinpoints regulators of cell size and the cell cycleMegan J Cully1 and Sally J Leevers2  1Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK 2Growth Regulation Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK  author email corresponding author email
Genome Biology 2006,
7:219doi:10.1186/gb-2006-7-5-219
Subject areas: Cell biology, Genome studies, Model organisms, Molecular biology Abstract
Cell-based genome-wide RNA interference screens are being used to address an increasingly broad spectrum of biological questions. In one recent screen, Drosophila cell cultures treated with double-stranded RNA were analyzed by flow cytometry, providing a wealth of new information and identifying 488 regulators of the cell cycle, cell size, and cell death. | 
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