Genome Biology
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MinireviewRNA interference pinpoints regulators of cell size and the cell cycleMegan J Cully1 and Sally J Leevers2  1
Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK 2
Growth Regulation Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK  author email corresponding author email
Genome Biology 2006,
7:219doi:10.1186/gb-2006-7-5-219
Subject areas: Cell biology, Genome studies, Model organisms, Molecular biology Abstract
Cell-based genome-wide RNA interference screens are being used to address an increasingly broad spectrum of biological questions. In one recent screen, Drosophila cell cultures treated with double-stranded RNA were analyzed by flow cytometry, providing a wealth of new information and identifying 488 regulators of the cell cycle, cell size, and cell death. | 
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