Predictive performance on biclusters representing key processes. Each plot shows a bicluster with a dominant functional theme from Figure 4. The red line indicates the measured expression profile, and the blue line shows the profile as predicted by the network model. Conditions in the left-most region of each plot were included in the bicluster, the middle regions show conditions excluded from the bicluster, and the right-most region of each plot corresponds to the 24 measurements that were not part of the original data set. The two right-most regions of each plot, therefore, demonstrate predictive power over conditions not in the training set. The estimation model parameters was done using only left-most/green conditions.
Bonneau et al. Genome Biology 2006 7:R36 doi:10.1186/gb-2006-7-5-r36