Genome Biology

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Inferring transcriptional modules from ChIP-chip, motif and microarray data

Karen Lemmens, Thomas Dhollander, Tijl De Bie, Pieter Monsieurs, Kristof Engelen, Bart Smets, Joris Winderickx, Bart De Moor and Kathleen Marchal*

Genome Biology 2006, 7:R37 doi:10.1186/gb-2006-7-5-r37

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Research   Open Access

TF-centered downstream gene set enrichment analysis: Inference of causal regulators by integrating TF-DNA interactions and protein post-translational modifications information

Qi Liu, Yejun Tan, Tao Huang, Guohui Ding, Zhidong Tu, Lei Liu, Yixue Li, Hongyue Dai, Lu Xie BMC Bioinformatics 2010, 11(Suppl 11):S5 (14 December 2010)

Research article   Open Access

Integrating functional genomics data using maximum likelihood based simultaneous component analysis

Robert A van den Berg, Iven Van Mechelen, Tom F Wilderjans, Katrijn Van Deun, Henk AL Kiers, Age K Smilde BMC Bioinformatics 2009, 10:340 (16 October 2009)

Research article   Open Access

A structured overview of simultaneous component based data integration

Katrijn Van Deun, Age K Smilde, Mariƫt J van der Werf, Henk AL Kiers, Iven Van Mechelen BMC Bioinformatics 2009, 10:246 (11 August 2009)

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An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules

Huaxia Qin, Michael WY Chan, Sandya Liyanarachchi, Curtis Balch, Dustin Potter, Irene J Souriraj, Alfred SL Cheng, Francisco J Agosto-Perez, Elena V Nikonova, Pearlly S Yan, Huey-Jen Lin, Kenneth P Nephew, Joel H Saltz, Louise C Showe, Tim HM Huang, Ramana V Davuluri BMC Systems Biology 2009, 3:73 (17 July 2009)

Research article   Open Access Highly Accessed

Transcriptional programs: Modelling higher order structure in transcriptional control

John E Reid, Sascha Ott, Lorenz Wernisch BMC Bioinformatics 2009, 10:218 (16 July 2009)

Method   Open Access

DISTILLER: a data integration framework to reveal condition dependency of complex regulons in Escherichia coli

Karen Lemmens, Tijl De Bie, Thomas Dhollander, Sigrid C De Keersmaecker, Inge M Thijs, Geert Schoofs, Ami De Weerdt, Bart De Moor, Jos Vanderleyden, Julio Collado-Vides, Kristof Engelen, Kathleen Marchal Genome Biology 2009, 10:R27 (6 March 2009)

DISTILLER, a data integration framework for the inference of transcriptional module networks, is presented and used to investigate the condition dependency and modularity in Escherichia coli networks.

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Gene set-based module discovery in the breast cancer transcriptome

Atsushi Niida, Andrew D Smith, Seiya Imoto, Hiroyuki Aburatani, Michael Q Zhang, Tetsu Akiyama BMC Bioinformatics 2009, 10:71 (26 February 2009)

Methodology article   Open Access

Systematic identification of yeast cell cycle transcription factors using multiple data sources

Wei-Sheng Wu, Wen-Hsiung Li BMC Bioinformatics 2008, 9:522 (5 December 2008)

Research article   Open Access Highly Accessed

Identifying gene regulatory modules of heat shock response in yeast

Wei-Sheng Wu, Wen-Hsiung Li BMC Genomics 2008, 9:439 (23 September 2008)

Research article   Open Access

Inferring transcriptional compensation interactions in yeast via stepwise structure equation modeling

Grace S Shieh, Chung-Ming Chen, Ching-Yun Yu, Juiling Huang, Woei-Fuh Wang, Yi-Chen Lo BMC Bioinformatics 2008, 9:134 (3 March 2008)

Research article   Open Access

Prioritization of gene regulatory interactions from large-scale modules in yeast

Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin Vingron BMC Bioinformatics 2008, 9:32 (22 January 2008)

Methodology article   Open Access Highly Accessed

Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana

Henning Redestig, Daniel Weicht, Joachim Selbig, Matthew A Hannah BMC Bioinformatics 2007, 8:454 (18 November 2007)

Research article   Open Access Highly Accessed

Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data

Xiangdong Liu, Walter J Jessen, Siva Sivaganesan, Bruce J Aronow, Mario Medvedovic BMC Bioinformatics 2007, 8:283 (3 August 2007)

Research   Open Access

Validating module network learning algorithms using simulated data

Tom Michoel, Steven Maere, Eric Bonnet, Anagha Joshi, Yvan Saeys, Tim Van den Bulcke, Koenraad Van Leemput, Piet van Remortel, Martin Kuiper, Kathleen Marchal, Yves Van de Peer BMC Bioinformatics 2007, 8(Suppl 2):S5 (3 May 2007)

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Clustering of genes into regulons using integrated modeling-COGRIM

Guang Chen, Shane T Jensen, Christian J Stoeckert Genome Biology 2007, 8:R4 (4 January 2007)

COGRIM, an implementation that integrates gene expression, ChIP binding and transcription factor motif data, is described and applied to both unicellular and mammalian organisms.