Table 1 |
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Correlation between enzymatic flux magnitude and evolutionary constraint Ka/Ks |
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| Uptake |
Maximum uptake rates (mmol/gDW/h) |
Spearman's rank correlation (P value) with zero fluxes |
Spearman's rank correlation (P value) without zero fluxes |
|
|
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| Glucose/oxygen |
15.3/2.4 |
-0.28 (P = 3.8 × 10-3) |
-0.25 (P = 3.6 × 10-6) |
|
|
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| Glucose/oxygen |
15.3/0.2 |
-0.31 (P = 1.7 × 10-3) |
-0.22 (P = 5.7 × 10-5) |
| Glucose/oxygen |
15.3/0.01 |
-0.26 (P = 9.3 × 10-3) |
-0.21 (P = 1.2 × 10-4) |
| Fructose/oxygen |
15.3/6.0 |
-0.27 (P = 6.4 × 10-3) |
-0.20 (P = 2.5 × 10-4) |
| Fructose/oxygen |
15.3/0.2 |
-0.25 (P = 1.3 × 10-2) |
-0.20 (P = 1.8 × 10-6) |
| Acetate/oxygen |
10.0/2.4 |
-0.08 (P = 0.45) |
-0.21 (P = 9.2 × 10-5) |
| Acetate/oxygen |
5.0/5.0 |
-0.010 (P = 0.39) |
-0.19 (P = 3.7 × 10-4) |
|
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The correlation between enzymatic flux magnitude and evolutionary constraint Ka/Ks was calculated with and without enzymes carrying zero fluxes. gDW, grams dry weight. |
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Vitkup et al. Genome Biology 2006 7:R39 doi:10.1186/gb-2006-7-5-r39 |
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