Table 5

Sum of the ranks of the exonic 4-mers at the donor and acceptor splice site of lost introns and simulated introns

Sum of the ranks

Donor site

Acceptor site

Lost introns*

6,737

6,410

Simulation average^†(std)

7,647 (253)

6,679 (337)

P value of lost introns^‡

0.0007

>0.05

*Sum of the ranks of the exonic 4-mers at the donor and acceptor splice site of the 34 lost introns. ^†A total of 10,000 iterations were generated. In each iteration, a total of 34 ranks were randomly generated according to the frequencies obtained from all the exonic 4-mers at the exon-intron boundaries of 33,011 FLS introns. Standard deviation is listed in the parenthesis. ^‡The P value for the sums of the ranks of the donor and acceptor splice site.

Lin et al. Genome Biology 2006 7:R41   doi:10.1186/gb-2006-7-5-r41