The subcellular localization of the mammalian proteome comes a fraction closer
Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
Genome Biology 2006, 7:222 doi:10.1186/gb-2006-7-6-222Published: 23 June 2006
Another step along the road towards determining the subcellular localization of a complete mammalian proteome has been taken with a study using cellular fractionation and protein correlation profiling to identify and localize organellar proteins. Here we discuss this new work in the context of other strategies for large-scale subcellular localization.