The subcellular localization of the mammalian proteome comes a fraction closer

doi:10.1186/gb-2006-7-6-222

Genome Biology

Volume 7
Issue 6

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The subcellular localization of the mammalian proteome comes a fraction closer

Jeremy C Simpson and Rainer Pepperkok

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany

author email corresponding author email

Genome Biology 2006, 7:222doi:10.1186/gb-2006-7-6-222


Published:	23 June 2006

Subject areas: Cell biology, Biochemistry and structural biology, Methods

Abstract

Another step along the road towards determining the subcellular localization of a complete mammalian proteome has been taken with a study using cellular fractionation and protein correlation profiling to identify and localize organellar proteins. Here we discuss this new work in the context of other strategies for large-scale subcellular localization.