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The elusive yeast interactome

Johannes Goll1 and Peter Uetz12*

Author Affiliations

1 Institut für Genetik, Forschungszentrum Karlsruhe, Box 3640, 76021 Karlsruhe, Germany

2 The Institute of Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA

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Genome Biology 2006, 7:223  doi:10.1186/gb-2006-7-6-223

Published: 30 June 2006

Abstract

Simple eukaryotic cells such as yeast could contain around 800 protein complexes, as two new comprehensive studies show. But slightly different approaches resulted in surprising differences between the two datasets, showing that more work is required to get a complete picture of the yeast interactome.