Open Access Research

Analysis of gene expression in operons of Streptomyces coelicolor

Emma Laing1,2, Vassilis Mersinias3, Colin P Smith3 and Simon J Hubbard1*

1 Faculty of Life Sciences, The University of Manchester, Manchester M13 9PT, UK

2 Current Address: School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK

3 Functional Genomics Laboratory, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK

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Genome Biology 2006, 7:R46 doi:10.1186/gb-2006-7-6-r46

Published: 2 June 2006

Additional files

Additional File 1:

Sixty-five E. coli genes found in our constructed data set of operons that have an experimentally validated upstream internal promoter.

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Open Data

Additional File 2:

The top table describes OIGs in E. coli found to have a putative TFBS site using our own PSWMs, their Zop,i score (in comparison to the first gene of the respective operon) and whether they are experimentally known (or computationally predicted); the bottom table describes E. coli OIGs predicted to have an upstream internal promoter using Li et al. [18] matrices.

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Open Data

Additional File 3:

SMD Experiment IDs used for S. coelicolor.

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Additional File 4:

Oklahoma database experiment IDs and SMD Experiment IDs used for E. coli.

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Additional File 5:

Experimentally validated operons used in this analysis for S. coelicolor.

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Open Data

Additional File 6:

Experimentally validated operons used in this analysis for E. coli.

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Open Data