Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling

doi:10.1186/gb-2006-7-6-r48

Genome Biology

Volume 7
Issue 6

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Zak DE
Hao H
Vadigepalli R
Miller GM
Ogunnaike BA
Schwaber JS

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Hao H
Vadigepalli R
Miller GM
Ogunnaike BA
Schwaber JS
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Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling

Daniel E Zak¹^,2^* , Haiping Hao¹^* , Rajanikanth Vadigepalli¹ , Gregory M Miller¹^,2 , Babatunde A Ogunnaike² and James S Schwaber¹

¹Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Thomas Jefferson University, Locust St, Philadelphia, PA, USA 19107

²Department of Chemical Engineering, University of Delaware, Academy St, Newark, DE, USA 19716

author email corresponding author email* Contributed equally

Genome Biology 2006, 7:R48doi:10.1186/gb-2006-7-6-r48


Published:	19 June 2006

Subject areas: Neurobiology, Cell biology

Additional files

Additional data file 1:

Gene expression boxplots for several genes with specific circadian time dependent EGF responses in the SCN.

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Additional data file 2:

Gene expression boxplots for the transcription factors investigated by qRT-PCR.

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Additional data file 3:

P values for EGF effects and EGF:CT interactions for all genes present on the microarrays of the current study.

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Additional data file 4:

P values for EGF effects and EGF:CT interactions for SCN circadian genes [17] present on the microarrays of the current study.

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Additional data file 5:

Detailed materials and methods.

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Additional data file 6:

Additional results.

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