Table 1

GO terms over-represented in the gene tiles enriched for human mutated sites (at sixfold over median threshold)

GO ID

GO Level

GO Term

P


GO:0007606

6,5

Sensory perception of chemical stimulus

1.21 e-43

GO:0007608

7,6

Sensory perception of smell

1.31 e-41

GO:0007600

5,4

Sensory perception

5.95 e-41

GO:0050877

4

Neurophysiological process

2.00 e-37

GO:0007186

6

G-protein-coupled receptor protein signaling pathway

3.48 e-30

GO:0050896

3

Response to stimulus

2.87 e-26

GO:0050874

3

Organismal physiological process

8.04 e-26

GO:0007166

5

Cell surface receptor linked signal transduction

8.05 e-23

GO:0007165

4

Signal transduction

6.26 e-15

GO:0007154

3

Cell communication

1.01 e-10

GO:0007582

2

Physiological process

9.89 e-04


GO, Gene Ontology.

Donaldson and Gƶttgens Genome Biology 2006 7:R52   doi:10.1186/gb-2006-7-6-r52

Open Data