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Targeting Drosophila eye development

Jennifer Jemc1 and Ilaria Rebay2 email

1Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA

2Ben May Institute for Cancer Research, University of Chicago, 929 E. 57th Street, Chicago, IL 60637, USA

author email corresponding author email

Genome Biology 2006, 7:226doi:10.1186/gb-2006-7-7-226

Published: 27 July 2006

Subject areas: Development, Model organisms, Genetics

Abstract

In order to understand the role of transcription factors in particular developmental processes it is necessary to know their target genes. A combination of bioinformatics, comparative expression profiling and microarray-based epistasis experiments has recently identified new targets of Eyeless, a key transcription factor in Drosophila retinal determination.


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