Genome Biology

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The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains

Lakshminarayan M Iyer, A Maxwell Burroughs and L Aravind*

Genome Biology 2006, 7:R60 doi:10.1186/gb-2006-7-7-r60

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Research article   Open Access

The phylogenomic analysis of the anaphase promoting complex and its targets points to complex and modern-like control of the cell cycle in the last common ancestor of eukaryotes

Laura Eme, Aurélie Trilles, David Moreira, Céline Brochier-Armanet BMC Evolutionary Biology 2011, 11:265 (23 September 2011)

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Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution

Thomas Cavalier-Smith Biology Direct 2010, 5:7 (4 February 2010)

This article is part of a collection on Evolutionary Biology 150...

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Reconstructing the ubiquitin network - cross-talk with other systems and identification of novel functions

Thiago M Venancio, S Balaji, Lakshminarayan M Iyer, L Aravind Genome Biology 2009, 10:R33 (30 March 2009)

A computational model of the yeast Ubiquitin system highlights interesting biological features including functional interactions between components and interplay with other regulatory mechanisms.

Discovery notes   Open Access

Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitination

Lakshminarayan M Iyer, AM Burroughs, L Aravind Biology Direct 2008, 3:45 (3 November 2008)

Research   Open Access

Small but versatile: the extraordinary functional and structural diversity of the β-grasp fold

A Maxwell Burroughs, S Balaji, Lakshminarayan M Iyer, L Aravind Biology Direct 2007, 2:18 (2 July 2007)

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A novel superfamily containing the β-grasp fold involved in binding diverse soluble ligands

A Maxwell Burroughs, S Balaji, Lakshminarayan M Iyer, L Aravind Biology Direct 2007, 2:4 (24 January 2007)