Genome Biology

official impact factor 6.89

Open Access Research

The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains

Lakshminarayan M Iyer1, A Maxwell Burroughs1,2 and L Aravind1*

Author Affiliations

1 National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, USA

2 Bioinformatics Program, Boston University, Cummington Street, Boston, Massachusetts 02215, USA

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Genome Biology 2006, 7:R60 doi:10.1186/gb-2006-7-7-r60

Published: 19 July 2006

Additional files

Additional data file 1:

complete list of conserved gene neighborhoods, domain architectures, and alignments discussed in this article.

Format: HTML Size: 579KB Download file

Open Data

Additional data file 2:

Complete list of all gi numbers for proteins encoded by conserved gene neighborhoods and their genomic position in various genomes.

Format: HTML Size: 1.2MB Download file

Open Data

Additional data file 3:

A list of major starting points for PSI-BLAST and HMMer searches and gi numbers detected in the searches conducted with them, along with e values.

Format: HTML Size: 2.9MB Download file

Open Data