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The cnidarian-bilaterian ancestor possessed at least 56 homeoboxes: evidence from the starlet sea anemone, Nematostella vectensis

Joseph F Ryan1,2 email, Patrick M Burton3 email, Maureen E Mazza3 email, Grace K Kwong3 email, James C Mullikin2 email and John R Finnerty1,3 email

1Bioinformatics Program, Boston University, Cummington Street, Boston, MA 02215, USA

2National Human Genome Research Institute, Fishers Lane, Bethesda, MD 20892, USA

3Department of Biology, Boston University, Cummington Street, Boston, MA 02215, USA

author email corresponding author email

Genome Biology 2006, 7:R64doi:10.1186/gb-2006-7-7-r64

Published: 24 July 2006

Subject areas: Evolution, Bioinformatics


Additional files

Additional data file 1:

Accession numbers and phylogenetic affinities are provided for each sequence, including the degree of statistical support for each homeodomain's phylogenetic position on both the neighbor-joining and Bayesian trees.

Format: PDF Size: 117KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 2:

Neighbor-joining phylogeny depicting the relationships among 455 distinct homeodomain sequences (130 from Nematostella, 97 from Drosophila, and 228 from human).

Format: PDF Size: 61KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 3:

Bayesian phylogeny depicting the relationships among the same 455 homeodomain sequences.

Format: PDF Size: 55KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 4:

Perl script that was used to parse BLAST reports and extract homeodomains from corresponding FASTA files.

Format: GZ Size: 553KB Download file

Additional data file 5:

Phylogenetic dataset used in this study in nexus format.

Format: NEX Size: 53KB Download file


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