Table 1

Number of homeodomain proteins by class, family, and species

Hs

Dm

Nv

CBA


ANTP class/Hox-related

CDX*

3

1

1

1

EVX*

2

1

1

1

EXEX*

1

1

1

1

GBX*

2

1

1

1

GSX*

2

1

1

1

HOX1*

3

1

2

1

HOX2*

2

1

3

1

HOX3*

3

3

0

0

HOX4*

4

1

0

0

HOX5*

3

1

0

0

HOX6-8*

8

3

0

0

HOX9-13*

16

1

0

0

IPF*

1

0

0

0

MOX*

2

1

4

1

ROUGH*

0

1

1

1

Unknown family

0

1

3

n/a

Total

52

19

18

9

ANTP class/other

BARH*

2

2

0

0

BARX

2

0

0

0

BSH*

1

1

0

0

CG13424*

0

1

2

1

DLX*

6

1

1

1

EMX*

2

2

2

1

EMXLX*

0

1

2

1

EN*

2

1

0

0

HHEX*

1

1

1

1

HLX*

2

2

7

1

HMX*

3

1

1

1

LBX*

2

2

1

1

MSX*

2

1

1

1

MSXLX*

0

1

2

1

NK1*

1

1

1

1

NK2*

7

2

5

1

NK3*

2

1

1

1

NK6*

2

1

1

1

NK7*

0

1

1

1

TLX*

3

1

1

1

VAX*

1

0

2

1

Unknown family

3

0

22

n/a

Total

44

24

54

17

CUT class

COMPASS

0

2

0

0

CUTL*

2

1

0

0

ONECUT*

3

1

0

0

SATB

2

0

0

0

Total

7

4

0

0

HNF

HNF1/2*

2

0

1

1

LIM class

AP*

2

1

0

0

ISLET*

2

1

1

1

LHX1/5*

2

1

1

1

LXH3/4*

2

1

0

0

LHX6/8*

2

1

1

1

LMX*

1

2

0

0

Unknown family

0

0

1

n/a

Total

11

7

4

3

POU class

POU1*

1

0

1

1

POU2*

3

2

0

0

POU3*

4

1

2

1

POU4*

3

1

1

1

POU5

2

0

0

0

POU6*

2

1

1

1

Total

15

5

5

4

PRD

AL*

1

2

1

1

ALX*

3

0

1

1

ANF

1

0

0

0

ARIX*

2

1

0

0

CEH10*

2

2

1

1

DMBX*

1

0

6

1

DUX*

20

0

3

1

GSC*

2

1

1

1

HB*

0

1

1

1

MIX

1

0

0

0

OTP*

1

1

1

1

OTX*

3

1

3

1

PAX3/7*

2

3

2

1

PAX4/6*

3

4

2

1

PRX*

2

1

0

0

PTX*

3

1

1

1

REPO*

0

1

1

1

RX*

2

1

1

1

SHOX

2

0

0

0

UNC4*

0

2

1

1

Unknown family

2

2

7

n/a

Total

53

24

33

15

PROS class

PROS

1

0

0

0

Total

1

0

0

0

SINE class

SIX1/2*

2

1

1

1

SIX3/6*

2

1

1

1

SIX4/5*

2

1

2

1

Unknown family

0

0

1

n/a

Total

6

3

5

3

TALE

IRX*

7

3

1

1

MEIS*

3

1

1

1

PBX*

4

1

1

1

TGIF*

1

2

1

1

Unknown family

1

0

2

n/a

TOTAL

16

7

6

4

ZF class

ZFHX2

2

0

0

0

ZFH4

2

0

0

0

ZHX

5

0

0

0

zfh1

0

1

0

0

zfh2*

1

1

0

0

Unknown family

1

0

0

n/a

Total

11

2

0

0

Unknown class

Total

10

2

4

n/a


*Counted as a shared family in Table 2. Absence of IPF in Drosophila is due to secondary loss. CBA, cnidarian-bilaterian ancestor; Hs, Homo sapiens; Dm, Drosophila melanogaster; Nv, Nematostella vectensis.

Ryan et al. Genome Biology 2006 7:R64   doi:10.1186/gb-2006-7-7-r64

Open Data