Table 2

Homeodomain families shared by two species but missing from the third (sorted by species and homeodomain class)

Class

Total number of shared families

Shared families missing in Hs

Shared families missing in Dm

Shared families missing in Nv


HOX

15*

1

1

6

other

20

4

1

3

CUT

2

0

0

2

HNF

1

0

1

0

LIM

6

0

0

3

POU

5

0

1

1

PRD

17

3

3

2

PROS

0

0

0

0

SINE

3

0

0

0

TALE

4

0

0

0

ZF

1

0

0

1

Total

73

8

7

18


*In the HOX class, IPF/XLOX is counted as a shared class because, even though it is not found in Drosophila, its presence in other protostome animals makes clear that its absence in the fruit fly is due to a secondary loss. Secondary loss of IPF/XLOX is known to have occurred in Drosophila. This gene is found in other protostome animals and so, while it is scored as missing from Drosophila, it is also regarded as a shared family among bilaterians that is missing in Nematostella. Hs, Homo sapiens; Dm, Drosophila melanogaster; Nv, Nematostella vectensis.

Ryan et al. Genome Biology 2006 7:R64   doi:10.1186/gb-2006-7-7-r64

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