Genome Biology

official impact factor 6.89

Open Access Research

Phylogenetically widespread alternative splicing at unusual GYNGYN donors

Michael Hiller1, Klaus Huse2, Karol Szafranski2, Philip Rosenstiel3,4, Stefan Schreiber3, Rolf Backofen1 and Matthias Platzer2*

Author Affiliations

1 Institute of Computer Science, Chair for Bioinformatics, Albert-Ludwigs-University Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany

2 Genome Analysis, Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr. 11, 07745 Jena, Germany

3 Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Schittenhelmstr. 12, 24105 Kiel, Germany

4 Max Planck Institute for Molecular Genetics, Ihnestr. 63, 14195 Berlin, Germany

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Genome Biology 2006, 7:R65 doi:10.1186/gb-2006-7-7-r65

Published: 25 July 2006

Additional files

Additional data file 1:

Data for all human confirmed GYNGYN splice donor sites identified in this study

Format: XLS Size: 22KB Download file

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Additional data file 2:

Data on the strength of e and i human GYNGYN donors

Format: XLS Size: 11KB Download file

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Additional data file 3:

Confirmed GYNGYN donors for seven species

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Additional data file 4:

Selected sequence traces that exemplify the experimental verification of GYNGYN donors

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Additional data file 5:

Control experiments for detecting minor splice forms by direct sequencing of RT-PCR products

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