Table 6

Category analysis

n

zmean

P

GO category

Description


113

2.5

2 × 10-19

5840 (CC)

Ribosome

81

1.8

4 × 10-9

5829 (CC)

Cytosol

45

2.8

1 × 10-8

0502 (CC)

Proteasome complex

284

1.2

3 × 10-18

6412 (BP)

Protein biosynthesis

96

0.9

1 × 10-5

6397 (BP)

mRNA processing

24

2.2

0.0002

4298 (MF)

Threonine endopeptidase activity

57

0.8

0.0009

8135 (MF)

Translation factor activity, nucleic acid binding


Selected GO categories whose member genes had particularly high z-scores. GO, Gene Ontology; n, number of genes annotated with that category and targeted by the RNAi library; P, P value for the null hypothesis that the mean z-score of the dsRNAs for this category is the same as that of all dsRNAs; RNAi, RNA interference; zmean, mean z-score.

Boutros et al. Genome Biology 2006 7:R66   doi:10.1186/gb-2006-7-7-r66

Open Data