Genome Biology

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Primate-specific evolution of an LDLR enhancer

Qian-fei Wang, Shyam Prabhakar, Qianben Wang, Alan M Moses, Sumita Chanan, Myles Brown, Michael B Eisen, Jan-Fang Cheng, Edward M Rubin* and Dario Boffelli

  • * Corresponding author: Edward M Rubin EMRubin@lbl.gov

  • † Equal contributors

Genome Biology 2006, 7:R68 doi:10.1186/gb-2006-7-8-r68

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Methodology article   Open Access Highly Accessed

Patterns of evolutionary constraints on genes in humans

Subhajyoti De, Nuria Lopez-Bigas, Sarah A Teichmann BMC Evolutionary Biology 2008, 8:275 (7 October 2008)

Research   Open Access

Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons

Qian-fei Wang, Shyam Prabhakar, Sumita Chanan, Jan-Fang Cheng, Edward M Rubin, Dario Boffelli Genome Biology 2007, 8:R1 (3 January 2007)

Intra-primate genome comparisons identify functional modules that are undetected by comparisons with non-mammalian genomes.