Research
Primate-specific evolution of an LDLR enhancer
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* Corresponding author: Edward M Rubin EMRubin@lbl.gov
- † Equal contributors
1 Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
2 US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
3 Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Genome Biology 2006, 7:R68 doi:10.1186/gb-2006-7-8-r68
Published: 2 August 2006Additional files
Additional data file 1:
A figure showing the conservation profiles of the LDLR locus using (A) human-dog and (B) human-lemur sequence comparisons.
Format: EPS Size: 1.9MB Download file
Additional data file 2:
A figure showing the DNaseI hypersensitive site mapping around the LDLR PS2 region in human liver cell line HepG2.
Format: EPS Size: 3.1MB Download file
Additional data file 3:
A figure showing that human LDLR PS2 enhancer activity is independent of the LDLR promoter.
Format: EPS Size: 2.3MB Download file
Additional data file 4:
A table listing the primers used in the cloning of human LDLR promoter and PS2 elements from indicated species.
Format: PDF Size: 11KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional data file 5:
A table listing the primers used in ChIP assay.
Format: PDF Size: 10KB Download file
This file can be viewed with: Adobe Acrobat Reader