Figure 1.

Model validation by comparing the R² for the real versus randomly permutated datasets. The R² obtained by applying the motif selection and fitting equation 2 (with sequence motif information only) procedures to randomly permutated and real data. The histogram is obtained based on 50 randomly permutated samples. The arrow on the right marks the R² for the real data. Results for the coding regions are represented here. See the main text for details.