Table 1

Correlation of tissue specificities measured by relative entropy in CAGE and UniGene EST clusters

Gene set

EST versus CAGE: Spearman rank correlation coefficient

Spearman rank correlation P value

Number of genes

Whole brain specific

216

1.10 × 10^-3

17

Testis specific

48

9.68 × 10^-2

9

Heart specific

40

1.48 × 10^-2

10

Liver specific

20,898

1.32 × 10^-6

66

Lung specific

92

1.81 × 10^-2

12

Cerebellum specific

186

<2.20 × 10^-16

20

Citric acid cycle

318

2.90 × 10^-1

14

Ubiquitin-mediated proteolysis pathway

886

5.94 × 10^-3

23

Housekeeping genes

2,208,352

8.54 × 10^-6

263

All sets combined

5,269,164

<2.20 × 10^-16

434

Pair-wise correlations between tissue specificity values using CAGE and EST clusters was calculated as in the cor.test method in the R language [62], using Spearman correlation (two-sided test). CAGE, cap analysis of gene expression; EST, expressed sequence tag.

Ponjavic et al. Genome Biology 2006 7:R78   doi:10.1186/gb-2006-7-8-r78