Functional genomics of the yeast DNA-damage response

Gerard Cagney¹, David Alvaro², Robert JD Reid², Peter H Thorpe², Rodney Rothstein² and Nevan J Krogan³^,4

¹Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland

²Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA

³Department of Cellular and Molecular Pharmacology, University of California-San Francisco, 1700 4th Street, San Francisco, CA 94143, USA

⁴California Institute for Quantitative Biomedical Research, University of California-San Francisco, 1700 4th Street, San Francisco, CA 94143, USA

author email corresponding author email

Genome Biology 2006, 7:233doi:10.1186/gb-2006-7-9-233


Published:	7 September 2006

Subject areas: Molecular biology, Genome studies, Cell biology, Genetics

Abstract

High-throughput approaches are beginning to have an impact on many areas of yeast biology. Two recent studies, using different experimental platforms, provide insight into new pathways involved in the response of yeast to DNA damage.