PhyloFacts: an online structural phylogenomic encyclopedia for protein functional and structural classification

Nandini Krishnamurthy , Duncan P Brown , Dan Kirshner and Kimmen Sjölander

Department of Bioengineering, 473 Evans Hall #1762, University of California, Berkeley, CA 94720, USA

author email corresponding author email

Genome Biology 2006, 7:R83doi:10.1186/gb-2006-7-9-r83


Published:	14 September 2006

Subject areas: Bioinformatics, Biochemistry and structural biology, Genome studies

Abstract

The Berkeley Phylogenomics Group presents PhyloFacts, a structural phylogenomic encyclopedia containing almost 10,000 'books' for protein families and domains, with pre-calculated structural, functional and evolutionary analyses. PhyloFacts enables biologists to avoid the systematic errors associated with function prediction by homology through the integration of a variety of experimental data and bioinformatics methods in an evolutionary framework. Users can submit sequences for classification to families and functional subfamilies. PhyloFacts is available as a worldwide web resource from http://phylogenomics.berkeley.edu/phylofacts webcite.