Figure 1.

PhyloFacts book: Voltage-gated K+ channels, Shaker/Shaw subtypes. Each book contains summary data at the top of the book page, including book type, number of sequences, number of predicted subfamilies, and taxonomic distribution. PFAM domains matching the book consensus sequence are displayed along with predicted transmembrane domains and signal peptides. Phylogenetic trees and multiple sequence alignments can be viewed or downloaded, for the family as a whole or for individual subfamilies. Predicted critical residues have been identified and are plotted on homologous PDB structures, where available (Figure 5). Clicking on 'View annotations and sequence headers' displays GO annotations and evidence codes for sequences in the family as a whole and for individual subfamilies.