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A correction for this article has been published in Genome Biology 2007, 8:401


Open AccessResearch

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

Katleen De Preter* 1 email, Jo Vandesompele* 1 email, Pierre Heimann2 email, Nurten Yigit1 email, Siv Beckman3 email, Alexander Schramm4 email, Angelika Eggert4 email, Raymond L Stallings5 email, Yves Benoit6 email, Marleen Renard7 email, Anne De Paepe1 email, Geneviève Laureys6 email, Sven Påhlman3 email and Frank Speleman1 email

1Center for Medical Genetics, Ghent University Hospital, De Pintelaan, B-9000 Ghent, Belgium

2Department of Medical Genetics, University Hospital Erasme, Lenniksebaan, B-1070 Brussels, Belgium

3Division of Molecular Medicine, Department of Laboratory Medicine, Lund University, University Hospital MAS, SE-20502 Malmö, Sweden

4Department of Pediatric Oncology and Hematology, University Hospital of Essen, Hufelandstr, Essen 45122, Germany

5Children's Cancer Research Institute, University of Texas Health Science Center, Floyd Curl Drive, Mail Code 7784, San Antonio, Texas 78229-3900, USA

6Department of Pediatrics, Ghent University Hospital, De Pintelaan, B-9000 Ghent, Belgium

7Department of Pediatrics, UZ Gasthuisberg, Herestraat, B-3000 Leuven, Belgium

author email corresponding author email* Contributed equally

Genome Biology 2006, 7:R84doi:10.1186/gb-2006-7-9-r84

Published: 21 September 2006

Subject areas: Cancer, Genome studies


Additional files

Additional data file 1:

RNA quality and quantity measures, validation of Affymetrix chip results, and Affymetrix chip quality parameters

Format: DOC Size: 1.4MB Download file

This file can be viewed with: Microsoft Word Viewer

Additional data file 2:

Genes that are differentially expressed in neuroblast versus cortex samples, in neuroblast versus favorable (F) and/or unfavorable (UF) neuroblastoma, and in favorable versus unfavorable neuroblastoma

Format: XLS Size: 349KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 3:

Results of NBGS analysis of the genes that are differentially expressed between neuroblasts and (favorable and/or unfavorable) neuroblastomas (gene lists in Additional data file 1)

Format: XLS Size: 56KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 4:

Genes of GO class neurogenesis and proneural genes that are expressed in neuroblast samples (> 36th percentile)

Format: XLS Size: 26KB Download file

This file can be viewed with: Microsoft Excel Viewer


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