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Highly Accessed Opinion

Genome re-annotation: a wiki solution?

Steven L Salzberg

Author affiliations

Center for Bioinformatics and Computational Biology and Department of Computer Science, 3125 Biomolecular Sciences Building, University of Maryland, College Park, MD 20742, USA

Citation and License

Genome Biology 2007, 8:102  doi:10.1186/gb-2007-8-1-102

Published: 1 February 2007

Abstract

The annotation of most genomes becomes outdated over time, owing in part to our ever-improving knowledge of genomes and in part to improvements in bioinformatics software. Unfortunately, annotation is rarely if ever updated and resources to support routine reannotation are scarce. Wiki software, which would allow many scientists to edit each genome's annotation, offers one possible solution.